New article accepted in Cell Biochemistry and Biophysics

Our new article entitled “Single Active Site Mutation Causes Serious Resistance of HIV Reverse Transcriptase to Lamivudine: Insight from Multiple Molecular Dynamics Simulations” accepted recently in Cell Biochemistry and Biophysics which unveils the HIV-1 reverse transcriptase’s mechanism of resistance to lamivudine due to M184I mutation. A multiple molecular dynamics simulation approach was employed in this regard to understand the biophysics.

Reference: Moonsamy S., Bhakat S., Walker R.C. and Soliman M.E. (2015) Single Active Site Mutation Causes Serious Resistance of HIV Reverse Transcriptase to Lamivudine: Insight from Multiple Molecular Dynamics Simulations, Cell Biochemistry and Biophysics, Accepted.